Hartert, Tina V., MD, MPH

Dr. Tina Hartert
Professor of Medicine. Director, Center for Asthma Research.  Assistant Vice Chancellor for Translational Science. Lulu H. Owen Chair in Medicine
Primary Department:
Department of Medicine, Vanderbilt Institute for Medicine & Public Health

Allergy, Pulmonary, and Critical Care Medicine


Office Address:
Vanderbilt University Medical Center
Division of Allergy, Pulmonary & Critical Care Medicine
Center for Health Services Research
Suite 6100 MCE
Nashville, TN 37232-8300
Office Phone:
Phone to Schedule:
Office Fax:
Undergraduate School & Degree:
Brown University, B.A.
Medical School & Degree:
Vanderbilt University School of Medicine, M.D.
Graduate School & Degree:
Vanderbilt University School of Medicine, M.P.H.
Board & Certifications:

Internal Medicine, Pulmonary, and Critical Care Medicine

Brief Bio:

Tina Hartert, MD, MPH received her BA with honors from Brown University, her MD and MPH from Vanderbilt University School of Medicine. She completed her Internal Medicine residency and chief residency at Johns Hopkins University School of Medicine, and her Pulmonary and Critical Care Medicine fellowship at Vanderbilt. She is a member of the scientific and medical honors societies, Sigma Xi, Alpha Omega Alpha, and was elected into the American Society of Clinical Investigation in 2009. She is currently a Professor of Medicine and the Director of the Center for Asthma Research, and serves the institution in the role of Assistant Vice Chancellor for Translational Science. She attends a weekly general pulmonary outpatient clinic at The Vanderbilt Clinic, and is an in-patient attending on the pulmonary and critical care services at Vanderbilt University Hospital.    

Dr. Hartert’s research focuses on asthma and allergic diseases, which are among the most common chronic diseases of both children and adults.  She firmly believes that the long-term solution to the asthma epidemic is primary and secondary disease prevention.  Thus, the major scientific programs of the Center for Asthma Research are to identify causal risk factors for asthma, understand their mechanism of action, and develop and test primary and secondary prevention strategies for asthma and allergic diseases.  The Center's current areas of focus for primary and secondary prevention include the role of early life respiratory tract infections, dietary factors, the microbiome, and medication exposures and utilization.  The Center is comprised of a group of highly collaborative and talented investigators, post-doctoral fellows, nurses, research assistants, and students who share a common goal to improve the health of people worldwide. Dr. Hartert is currently supported by several extramural NIH research grants as well as an NIH mid-career investigator award.


Asthma; pulmonary diseases; critical care.

Research Focus:

 Asthma epidemiology; asthma in high-risk populations; primary disease prevention; asthma risk factors; public health.


Selected peer-reviewed publications.
( * indicates individual for whom Dr. Hartert serves/d as primary mentor)

Arnold, DH, Gebretsadik, T, Hartert, TV. Spirometry and PRAM Severity Score Changes During Pediatric Acute Asthma Exacerbation Treatment in a Pediatric Emergency Department. J Asthma, 50(2), 204-8, 2013.

*Carroll, KN, Hartert, TV. Reply. J Allergy Clin Immunol, 131(2), 616-7, 2013.

James, KM, Gebretsadik, T, Escobar, GJ, Wu, P, Carroll, KN, Li, SX, Walsh, EM, Mitchel, EF, Sloan, C, Hartert, TV. Risk of childhood asthma following infant bronchiolitis during the respiratory syncytial virus season. J Allergy Clin Immunol, , , 2013.

Arnold, DH, Gebretsadik, T, Abramo, TJ, Hartert, TV. Noninvasive testing of lung function and inflammation in pediatric patients with acute asthma exacerbations. J Asthma, 49(1), 29-35, 2012.

Arnold, DH, Gebretsadik, T, Abramo, TJ, Sheller, JR, Resha, DJ, Hartert, TV. The Acute Asthma Severity Assessment Protocol (AASAP) study: objectives and methods of a study to develop an acute asthma clinical prediction rule. Emerg Med J, 29(6), 444-50, 2012.

*Carroll, KN, Gebretsadik, T, Minton, P, Woodward, K, Liu, Z, Miller, EK, Williams, JV, Dupont, WD, Hartert, TV. Influence of maternal asthma on the cause and severity of infant acute respiratory tract infections. J Allergy Clin Immunol, 129(5), 1236-42, 2012.

Carroll, KN, Griffin, MR, Edwards, KM, Ali, A, Zhu, Y, Iwane, MK, Szilagyi, PG, Staat, MA, Stevens, TP, Hall, CB, Williams, JV, Hartert, TV. Adherence to guidelines for respiratory syncytial virus immunoprophylaxis among infants with prematurity or chronic lung disease in three United States counties. Pediatr Infect Dis J, 31(11), e229-31, 2012.

Hayes, RM, Wu, P, Shelton, RC, Cooper, WO, Dupont, WD, Mitchel, E, Hartert, TV. Maternal antidepressant use and adverse outcomes: a cohort study of 228,876 pregnancies. Am J Obstet Gynecol, 207(1), 49.e1-9, 2012.

James, KM, Peebles, RS, Hartert, TV. Response to infections in patients with asthma and atopic disease: an epiphenomenon or reflection of host susceptibility. J Allergy Clin Immunol, 130(2), 343-51, 2012.

Klemenc, J, Asad Ali, S, Johnson, M, Tollefson, SJ, Talbot, HK, Hartert, TV, Edwards, KM, Williams, JV. Real-time reverse transcriptase PCR assay for improved detection of human metapneumovirus. J Clin Virol, 54(4), 371-5, 2012.

Ali, SA, Gern, JE, Hartert, TV, Edwards, KM, Griffin, MR, Miller, EK, Gebretsadik, T, Pappas, T, Lee, WM, Williams, JV. Real-world comparison of two molecular methods for detection of respiratory viruses. Virol J, 8, 332, 2011.

Arnold, DH, Gebretsadik, T, Abramo, TJ, Moons, KG, Sheller, JR, Hartert, TV. The RAD score: a simple acute asthma severity score compares favorably to more complex scores. Ann Allergy Asthma Immunol, 107(1), 22-8, 2011.

*Carroll, KN, Gebretsadik, T, Larkin, EK, Dupont, WD, Liu, Z, Van Driest, S, Hartert, TV. Relationship of maternal vitamin D level with maternal and infant respiratory disease. Am J Obstet Gynecol, 205(3), 215.e1-7, 2011.

Larkin, EK, Gebretsadik, T, Koestner, N, Newman, MS, Liu, Z, Carroll, KN, Minton, P, Woodward, K, Hartert, TV. Agreement of blood spot card measurements of vitamin D levels with serum, whole blood specimen types and a dietary recall instrument. PLoS One, 6(1), e16602, 2011.

Miller, EK, Williams, JV, Gebretsadik, T, Carroll, KN, Dupont, WD, Mohamed, YA, Morin, LL, Heil, L, Minton, PA, Woodward, K, Liu, Z, Hartert, TV. Host and viral factors associated with severity of human rhinovirus-associated infant respiratory tract illness. J Allergy Clin Immunol, 127(4), 883-91, 2011.

Valet, RS, Gebretsadik, T, Carroll, KN, Wu, P, Dupont, WD, Mitchel, EF, Hartert, TV. High asthma prevalence and increased morbidity among rural children in a Medicaid cohort. Ann Allergy Asthma Immunol, 106(6), 467-73, 2011.

*Wu, P, Hartert, TV. Evidence for a causal relationship between respiratory syncytial virus infection and asthma. Expert Rev Anti Infect Ther, 9(9), 731-45, 2011.

Arnold, DH, Jenkins, CA, Hartert, TV. Noninvasive assessment of asthma severity using pulse oximeter plethysmograph estimate of pulsus paradoxus physiology. BMC Pulm Med, 10, 17, 2010.

Deng, X, Gebretsadik, T, Jin, M, Gao, YT, Bai, C, Christman, JW, Wen, W, Dupont, WD, Plummer, D, Stephens, J, Shu, XO, Hartert, TV. Development of a nomogram for identification of asthma among adults in epidemiologic studies. Ann Allergy Asthma Immunol, 105(3), 203-10, 2010.

Hartert, TV, Carroll, K, Gebretsadik, T, Woodward, K, Minton, P, , . The Tennessee Children''s Respiratory Initiative: Objectives, design and recruitment results of a prospective cohort study investigating infant viral respiratory illness and the development of asthma and allergic diseases. Respirology, 15(4), 691-9, 2010.

*Carroll KN, *Wu P, Gebretsadik T, Griffin MR, Dupont WD, Mitchel EF, Hartert TV. The Severity-Dependent Relationship of Infant Bronchiolitis on the Risk and Morbidity of Early Childhood Asthma J Allergy Clin Immunol. 2009;123(5):1055-61.

*Wu P, Dupont W, Griffin M, Carroll K, Mitchel E, Gebretsadik T, Hartert T. Evidence of a causal role of winter virus infection during infancy on early childhood asthma. Am J Respir Crit Care Med. 178(11):1123-1129, 2008.

*Carroll KN, Gebretsadik T, Griffin MR, Wu P, Dupont WD, Mitchel EF, Enriquez R, Hartert TV. Increasing burden and risk factors for bronchiolitis-related medical visits in infants enrolled in a state healthcare insurance plan. Pediatrics. 122(1):58-64, 2008.

*Enriquez R, Griffin M, Carroll K, *Wu P, Cooper W, Gebretsadik T, Dupont W, Mitchel E, Hartert T. Effect of Maternal Asthma and Asthma Control on Pregnancy and Perinatal Outcomes. J Allergy Clin Immunol. 2007;120(3):625-30.

*Enriquez R, Persky V, Hartert T. Trends in Asthma Prevalence and Recommended Number of Childhood Immunizations are Not Parallel. Pediatrics. 119;222-223, 2007.  Free Article

 *Venarske DL, Busse WW, Griffin MR, Gebretsadik T, Shintani AK, Minton PA, Peebles SR Jr, Hamilton R, Weisshaar E, Vrtis R, Higgins SB, Hartert TV, The relationship of rhinovirus-associated asthma hospitalizations with inhaled corticosteroids and smoking. J Infect Dis. 193(11):1536-1543, 2006.  Free Article

 *Enriquez R, *Wu P, Griffin MR, Gebretsadik T, Shintani A, Mitchel E, Carroll KN, Hartert TV. Cessation of asthma medication in early pregnancy. Am J Obstet Gynecol. 195(1):149-153, 2006.

Williams JV, Crowe J, *Enriquez R, Minton P, Peebles RS, Hamilton RG, Higgins S, Griffin MR, Hartert TV. Human metapneumovirus infection plays an etiologic role in acute asthma hospitalizations in adults. J Infect Dis 192(7):1149-1153, 2005.  Free PMC Article

Talbot TR, Hartert TV, Mitchel E, Halasa NB, Arbogast PG, Poehling KA, Schaffner W, Craig AS, Griffin MR. Asthma as a risk factor for invasive pneumococcal disease. N Engl J Med. 19;352(20):2082-2090, 2005.  Free full text

Hartert TV, Neuzil KM, Shintani AK, Mitchel EF Jr, Snowden MS, Wood LB, Dittus RS, Griffin MR. Maternal morbidity and perinatal outcomes among pregnant women with respiratory hospitalizations during influenza season. Am J Obstet Gynecol. 189(6):1705-1712, 2003.

Hartert, Tina V. Acute asthma care interventions in improving asthma outcomes: putting guidelines into action. Ann Allergy Asthma Immunol, 90(1), 8-9, 2003.

Hartert, Tina V, Neuzil, Kathleen M, Shintani, Ayumi K, Mitchel, Edward F, Snowden, Mary S, Wood, Lesa B, Dittus, Robert S, Griffin, Marie R. Maternal morbidity and perinatal outcomes among pregnant women with respiratory hospitalizations during influenza season. Am J Obstet Gynecol, 189(6), 1705-12, 2003.

Hartert, Tina V, Speroff, Theodore, Togias, Alkis, Mitchel, Edward F, Snowden, Mary S, Dittus, Robert S, Griffin, Marie R. Risk factors for recurrent asthma hospital visits and death among a population of indigent older adults with asthma. Ann Allergy Asthma Immunol, 89(5), 467-73, 2002.

Hashimoto, K, Peebles, R S, Sheller, J R, Jarzecka, K, Furlong, J, Mitchell, D B, Hartert, T V, Graham, B S. Suppression of airway hyperresponsiveness induced by ovalbumin sensitisation and RSV infection with Y-27632, a Rho kinase inhibitor. Thorax, 57(6), 524-7, 2002. PMCID:1746359

Lefebvre, Jean, Murphey, Laine J, Hartert, Tina V, Jiao Shan, Ru, Simmons, William H, Brown, Nancy J. Dipeptidyl peptidase IV activity in patients with ACE-inhibitor-associated angioedema. Hypertension, 39(2 Pt 2), 460-4, 2002.

Peebles, R Stokes, Hartert, Tina V. Highlights from the annual scientific assembly: patient-centered approaches to asthma management: strategies for treatment and management of asthma. South Med J, 95(7), 775-9, 2002.

Dworski, R, Roberts, L J, Murray, J J, Morrow, J D, Hartert, T V, Sheller, J R. Assessment of oxidant stress in allergic asthma by measurement of the major urinary metabolite of F2-isoprostane, 15-F2t-IsoP (8-iso-PGF2alpha). Clin Exp Allergy, 31(3), 387-90, 2001.

Hartert, T V, Peebles, R S. Dietary antioxidants and adult asthma. Curr Opin Allergy Clin Immunol, 1(5), 421-9, 2001.

Hartert, T V, Dworski, R T, Mellen, B G, Oates, J A, Murray, J J, Sheller, J R. Prostaglandin E(2) decreases allergen-stimulated release of prostaglandin D(2) in airways of subjects with asthma. Am J Respir Crit Care Med, 162(2 Pt 1), 637-40, 2000.

Hartert, T V, Peebles, R S. Epidemiology of asthma: the year in review. Curr Opin Pulm Med, 6(1), 4-9, 2000.

Hartert, T V, Togias, A, Mellen, B G, Mitchel, E F, Snowden, M S, Griffin, M R. Underutilization of controller and rescue medications among older adults with asthma requiring hospital care. J Am Geriatr Soc, 48(6), 651-7, 2000.

Peebles, R S, Hartert, T V. Respiratory viruses and asthma. Curr Opin Pulm Med, 6(1), 10-4, 2000.

Hartert, T V, Wheeler, A P, Sheller, J R. Use of pulse oximetry to recognize severity of airflow obstruction in obstructive airway disease: correlation with pulsus paradoxus. Chest, 115(2), 475-81, 1999.

Peebles, R S, Hartert, T V, Sheller, J R. Viral infections in asthma. Compr Ther, 24(10), 511-8, 1998.

Peebles, R S, Hartert, T V. In vivo diagnostic procedures: skin testing, nasal provocation, and bronchial provocation. Methods, 13(1), 14-24, 1997.

Hartert, T V, Windom, H H, Peebles, R S, Freidhoff, L R, Togias, A. Inadequate outpatient medical therapy for patients with asthma admitted to two urban hospitals. Am J Med, 100(4), 386-94, 1996.

Heldman, A W, Hartert, T V, Ray, S C, Daoud, E G, Kowalski, T E, Pompili, V J, Sisson, S D, Tidmore, W C, vom Eigen, K A, Goodman, S N, Lietman, P S, Petty, B G, Flexner, C. Oral antibiotic treatment of right-sided staphylococcal endocarditis in injection drug users: prospective randomized comparison with parenteral therapy. Am J Med, 101(1), 68-76, 1996.