Recent Grant Awards in the Department of Medicine

Updated: 10/25/2018

NIH AWARDS (New, Competing)


Principal Investigator(s)

Agency Serial

Budget Start Date

Project Title

GE Ruderfer, Doug 1R01MH116269-01A1  02/05/2019 2/2 Leveraging electronic health records for pharmacogenomics of psychiatric disorders
GE Southard-Smith, Michelle 1R01DK120025-01  02/01/2019 Serotonin signaling in control of the Lower Urinary Tract
NP Harris, Ray (Contact); Mingzhi Zhang 2R01DK062794-16A1  02/01/2019 The Role of Cyclooxygenase-2 in Salt-Sensitive Hypertension
CP Phillips, Elizabeth 1R13AR074889-01  01/25/2019 Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis 2019: From Science to Translation
RH Aune, Thomas 1R21AI144193-01  01/15/2019 Alu RNAs and double-stranded RNA sensors
EP Shu, XIAO-Ou 1R01CA227133-01A1 01/01/2019 Use of Circulating MicroRNAs for Early Detection and Risk Assessment for Pancreatic Cancer
IM Roumie, Christianne 1K12HS026395-01 09/30/2018 Learning Health System Scholar Program at Vanderbilt
NP Pozzi, Ambra 1R01DK119212-01 09/25/2018 Matrix receptors in chronic kidney disease
GI Coffey, Robert (contact); Shrubsole, Martha; Lau, Ken 1U2CCA233291-01 09/20/2018 Integrative Single-Cell Atlas of Host and Microenvironment in Colorectal Neoplastic Transformation
HO Warner, Jeremy 1U01CA231840-01 09/18/2018 Network Analysis for a Data-Driven Approach to Cancer Care
GR Dugan, Laura 1R01AG058856-01 09/15/2018 Inflammatory Mechanisms Underlie Lysosome Failure in the Aging Brain
CA Moslehi, Javed 1R56HL141466-01 09/15/2018 Novel mechanisms and predictors of VEGF receptor inhibitor-associated
CP Perrien, Dan 1R01AR073874-01 09/10/2018 The contribution of innate immunity to heterotopic ossification in fibrodysplasia ossificans progressiva
EP Guo, Xingyi 1R37CA227130-01A1 09/04/2018 Transcriptome-wide association study to identify susceptibility genes for colorectal cancer
CA Diedrich, Andre 1R56HL142583-01 09/01/2018 Autonomic Determinants of Postural Tachycardia Syndrome
CA Chung, Cecilia 1R01GM126535-01A1 09/01/2018 A Personalized Medicine Approach to Improve the Prediction of Azathioprine Toxicity
NP Umeukeje, Ebele 1K23DK114566-01A1 09/01/2018 Patient-centered Approach To Improving Dialysis Adherence in African Americans
CA Collins, Sheila 1R01DK116625-01 08/22/18 Dissecting PKA activation of mTORC1 and its function in adipose tissue
CA Freiberg, Matt 1K12HL143956-01 08/15/18 Vanderbilt SCHolars in HIV and Heart, Lung, Blood, and Sleep ReSearch (VSCHoLARS, K12)
AP Hartert, Tina 1R01AI136526-01A1 08/07/18 Leukotriene modifying agents in the prevention of excess morbidity and mortality from influenza
EP Yu, Danica 1R21HL140375-01A1 08/05/18 Levels of trimethylamine metabolites and their associations with dietary intakes and cardiometabolic biomarkers: the TMAO Pooling Project
ID Sterling, Tim 1R56AI118361-01A1 08/03/18 Fluoroquinolones and Efflux-Mediated Cross Resistance in HIV-related TB
AP Cahil, Katherine 7K23AI118804-05 08/01/18 The Role Of Prostaglandin D2 In The Respiratory Symptoms Of
Aspirin Exacerbated Respiratory Disease
NP Harris, Ray 2R01NR015079-05 08/01/18 Imaging Biomarkers of Lymphatic Dysfunction
NP Abdel-Kader, Khaled 1R01DK116957-01A1 08/01/18 PopulAtioN health management to OPTImize Care in CKD (PANOPTIC-CKD)
DE Dean, Erica Danielle 1K01DK117969-01 08/01/18 Amino acid regulation of pancreatic islet alpha cell proliferation and function
HO Rathmell, Kim 1T32CA217834-01A1 08/01/18 VIMORTP (Vanderbilt Integrated Molecular Oncology Research Training Program)
CO Luther, James M 1R01DK117875-01 08/01/18 Variation in Soluble Epoxide Hydrolase Activity and Human Insulin Sensitivity
CA Ferguson, Jan 1R01DK117144-01A1 08/01/18 Determinants of alpha-aminoadipic acid (2-AAA) and relationship to diabetes
GE Below, Jennifer (contact); Kraft, Shelly Jo 1R01DC017175-01  08/01/18 Developmental stuttering: Population-based genetic discovery
AP Semler, Matt 1K23HL143053-01 07/05/18 Oxygen Saturation Targets during Mechanical Ventilation of Critically Ill Adults: A Clinical Trial
IM Roumie, Christianne (contact); Grijalva, Carlos 1T32HS026122-01 07/01/2018 Learning Health System training program: PROgRESS--Patient/ pRactice Outcomes and Research in Effectiveness and Systems Science
AP Blackwell, Timothy S 2T32HL094296-11 07/01/2018 Interdisciplinary Training Program in Lung Research
CP Phillips, Elizabeth 1R34AI136815-01 06/22/2018 NATIENS: A Phase III Randomized Study to Determine the Mechanisms and Optimal Management of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
CP Phillips, Elizabeth 1R21AI139021-01 06/22/2018 Single Cell definition of pathogenic T cells in Drug-induced Stevens-Johnson-Syndrome/Toxic epidermal necrolysis
AP Majka, Sue 2R01HL116597-05A1 06/01/2018 Role of Lung MSC in Emphysema

Barnado, April



Using the electronic health record to risk-stratify patients with systemic lupus erythematosus

HO Zinkel, Sandra 1R01HL133559-01A1 05/03/2018 Mechanism of necrosis regulation of hematopoietic stem cell function
DE Powers, Al 2T35DK007383-39 05/01/2018 Vanderbilt Student Research Training Program
NP Gautam, Bhave 1R01DK116964-01 05/01/2018 The Role of Hypobromous Acid in Renal Disease
HO Engelhardt, Brian 1R01HL141943-01 04/15/2018 Islet Cell and ST2 Axis Dysregulation in Post-Transplant Diabetes Mellitus
NP Haase, Volker 2R01DK081646-10A1 04/03/2018 Molecular Mechanisms of Renal Injury
GI Peek, Rich 2R01CA077955-22 04/01/2018 H. Pylori Relationship to Digestive Diseases and Cancer
NP Hudson, Billy 2R25DK096999-07 04/01/2018 Aspirnaut Undergraduate Discovery Science Experience in Renal Biology and Disease
EP Kuhs, Krystle 1K07CA218247-01A1  04/01/2018 Human Papillomavirus-Specific Biomarkers for the Prediction of Oropharyngeal Cancer Recurrence
EP Sudenga, Staci 1K07CA225404-01A1 04/01/2018 Tumor-Infiltrating Lymphocytes in Anal Cancer and Pre-malignant Anal Lesions
EP Lang, Wu 1K99CA218892-01A1 04/01/2018 Uncovering roles of polyunsaturated fatty acids in pancreatic cancer etiology
ID Aronoff, David 1U01TR002398-01 03/15/2018 Repurposing misoprostol to prevent recurrence of Clostridium difficile infection

Other AWARDS (New, Competing)



Principal Investigator(s)

Agency Serial

Start Date


Department of Defense CP Johnson, Rachelle W W81XWH-18-1-0029 9/30/2018 Targeting histone modifications to promote LIFR and tumor dormancy
Foundation for Sarcoidosis Research ID Chioma, Ozioma S   7/2/2018 Investigation of Pulmonary Sarcoidosis Microbiome According to Clinical Outcome
Congressionally Directed Medical Research Programs HO Balko, Justin Micah W81XWH-18-1-0149 6/15/2018 Translating immunotherapy to breast cancer: mechanisms, biomarkers, and rationally-designed therapeutic combinations
International Association for the Study of Lung Cancer HO Beckermann, Kathryn E (Rathmell) LCFA-IASLC-BMS 4/1/2018 Single cell analysis to understand the biology of response to immunotherapy in lung cancer
American Heart Association CA Beckman, Joshua A 18SFRN33900069 4/1/2018 Microcirculatory Disease Determines Limb Outcomes in PAD
American Heart Association CA Beckman, Joshua A 18SFRN33960373 4/1/2018 The Impact of Branched-Chain Amino Acids Metabolism on Limb Dysfunction in PAD
American Heart Association CA Freiberg, Matthew S 18SFRN3397011 4/1/2018 Clinical and genetic determinants of peripheral artery disease, microvascular disease, and major adverse limb outcomes
International Association for the Study of Lung Cancer HO Lovly, Christine M   2/1/2018 Understanding dynamic somatic genomic changes and hereditary predisposition in patients with small cell lung cancer
Society of Critical Care Medicine AP Sevin, Carla M   1/9/2018 Collaborative Assessment of ICU Recovery Needs (CAIRN)
Gilead AP Noto, Michael J   1/2/2018 Enhanced lung defenses stimulated by A. baumannii
American Diabetes Association CA Shi, Fubiao  (Collins) 1-18-PDF-110 1/1/2018 Deciphering the metabolic benefits of NPRC deficiency in adipose tissues during diet-induced obesity and cold acclimation
American Diabetes Association NP Chen, Jianchun     1/1/2018 Alterations of the Hippo Signaling Pathway in Diabetic Nephropathy
Melanoma Research Foundation HO Johnson, Douglas B   1/1/2018 Comprehensive profiling of immune checkpoint inhibitor colitis
PhRMA Foundation CP Blackwell, Daniel     1/1/2018 Mechanisms of arrhythmogenic calcium release inhibition by flecainide and a novel synthesized depsipeptide-PhRMA Foundation Post Doctoral Fellowship A