Recent Grant Awards in the Department of Medicine

Updated: 9/19/2017

NIH AWARDS (New, Competing)

Division

Principal Investigator(s)

Agency Serial

Budget Start Date

Project Title

EP

Khankari, Nikhil

1K99CA215360-01A1

09/18/17 Polyunsaturated fatty acids and colorectal tumor risk: a molecular and genetic epidemiology study

AP

Loyd, James

2P01HL108800-07

09/15/17

Hormonal, Metabolic and Signaling Interactions in PAH

NP

Harris, Ray

1P30DK114809-01

09/08/17

Vanderbilt O'Brien Kidney Center

ID

Gaddy, Jennifer

1R01HD090061-01A1

09/01/17

Determining the contribution of zinc deficiency to perinatal Group B Streptococcus infections

GI

Goettel, Jeremy

7K01DK106311-03

09/01/17 Investigating cross-regulation of the microbiome and mucosal immune system using humanized mice

BI

Peterson, Josh

1R01HG009694-01

09/05/17

Rational Integration of clinical SEquencing (RISE)

CA

Young-Jae, Nam

1R03HL140264-01

09/15/17

Defining cardiomyocyte reprogramming induced heart repair

NP

Birdwell, Kelly

1U01DK116093-01

09/25/17 APOL1 and Kidney Transplantation Outcomes Vanderbilt Clinical Center

IM

Kripalani, Sunil (contact); Roumie, Christianne​

1K12HL137943-01

09/01/17 Vanderbilt Scholars in T4 Translational Research
(V-STTaR) Program

GR

Wilkins, Consuelo 1R13TR001694-01A1 09/01/17

Advancing the Science of Community Engaged Research

EP

Shu, Xioa-Ou 2T32CA160056-07 09/01/17 Vanderbilt Training Program in Molecular and Genetic Epidemiology of Cancer

AP

Richmond, Bradley 1K08HL138088-01 09/01/17 Role of p73 in COPD Pathogenesis

ID

Aronoff, David 1R01AI134036-01 08/18/17 The Role of macrophages in chorioamnionitis and group B streptococcal infections
EP Wu, Pingsheng  1R21HL133742-01 08/05/17 Antibiotic timing, spectrum, and cumulative dose during pregnancy and infancy on risk of asthma
GI Peek, Rick 2P30DK058404-16 08/01/17 MOLECULAR AND CELLULAR BASIS FOR DIGESTIVE DISEASES
CA Brittain, Evan 1R34HL136989-01 08/01/17  Mobile Health Intervention in Pulmonary Arterial Hypertension
CA Freiberg, Matt 1U01AA026222-01 08/01/17 1/2 Alcohol Associated Comorbidities and Microbiome Evaluation in HIV (ACME HIV)
AP Ware, Lorraine (contact); Bastarache, Julie 1R01HL135849-01A1 08/01/17 Targeting cell-free hemoglobin in sepsis to reduce lung microvascular permeability: mechanistic and translational studies
RH Aune, Thomas 1R21AI128281-01A1 08/01/17 LncRNAs tether transcription factors to enable locus-specific regulation and sustain memory T cell phenotype
HO Ferrell, Brent 1K23HL138291-01 08/01/17 Investigating the role of the JAK/STAT3 Pathway in Clonal Proliferation and Immune Dysfunction in Myelodysplastic Syndrome
GE Knapik, Ela (contact: Cox, Nancy; Sutcliffe, James 1R01MH113362-01 08/01/17 Discovering Biology for Neuropsychiatric Diseases Through Omics Studies on Comorbidities
NP Zent, Roy 1R13AR072495-01 07/20/17 ASMB/Vanderbilt Workshop on Basement Membranes
CA Hatzopoulos, Antonis 1R01HL138519-01 07/15/17 Functional heterogeneity of cardiac reparative cells after injury
CA Gumina, Richard 1R01HL127442-01A1 7/14/2017 Ectonucleotidases in ischemic heart disease
ID Rebeiro, Peter 1K01AI131895-01A1 7/5/2017 The HIV Care Continuum and Health Policy: Changes through Context and Geography
GE Pal, Tuya 1R01CA204819-01A1 7/1/2017 Breast Cancer In Blacks: Impact of Genomics, Healthcare Use and Lifestyle on Outcomes (BRIGHT)
CA Becker, Jason 1R01HL136824-01A1 7/1/2017 Cell State Specific Modifiers of Pathological Cardiac Remodeling
CP Stein, C. Michael 2T32GM007569-42 7/1/2017 Clinical Pharmacology Training Program
AP Carrier, Erica 1R01HL135011-01A1 7/01/2017 Role of the thromboxane prostanoid receptor in right ventricular adaptation to pressure overload
DE Powers, Al 2P30DK020593-40 6/16/2017 Vanderbilt Diabetes Research and Training Center
EP Dai, Qi 1R01DK110166-01A1 5/5/2017 Calcium: magnesium balance, microbiota, and necroptosis and inflammation
AP Shaver, Ciara 1K08HL136888-01 5/1/2017 Mechanisms of airspace inflammation caused by cell-free hemoglobin during ARDS
AP Bernard, Gordon 2T32HL087738-12 5/1/2017 Clinical and Translational Training Program in Pulmonary Medicine
CP Glazer, Andrew 1F32HL137385-01 By: 9/30/2017 High-throughput Discovery of Pathogenic Cardiac Sodium Channel Variants
ID Smith, Scott 1R01AI130459-01 4/6/2017 Antigenic landscape of the human helminth IgE antibody response
GI Coffey, Bob 1R35CA197570-01A1 4/1/2017 Integrated approach to study early and late events in colonic neoplasia: mouse to man
CP Murray, Kathy 1R01HL133127-01A1 4/1/2017 Novel Pathophysiological Targets in Atrial Fibrillation Susceptibility
NP de Caestecker, Mark 1R01DK112688-01A1 4/1/2017 Mechanisms and therapeutic manipulation of retinoic acid signaling in Acute Kidney Injury
IM Mayberry, Lindsay 1R03DK113329-01 3/1/2017 Diabetes-Specific Family Functioning among Adults: Types, Predictors, and Outcomes
ID Koethe, John 1R01DK112262-01 2/15/2017 The Role of Adipose-resident T cells in HIV-associated Glucose Intolerance
CP Kroncke, Brett 1K99HL135442-01 2/15/2017 SCN5A (Nav1.5): Predicting the Consequence of Missense Single- Nucleotide
ID Phillips, Elizabeth 1R13AR071267-01 2/1/2017 Stevens-Johnson Syndrome/Toxic Epidural Necrolysis 2017: Building Multidisciplinary Networks to Drive Science and Translation
CA Lal, Hind 1R01HL133290-01A1 2/1/2017 Signaling mechanisms governing myocardial fibrosis in diseased heart
NP Hudson, Billy 2R01DK065138-15A1 2/1/2017 Glucose Modifications of Proteins in Diabetic Nephropathy
CP Gomez, Jose 1K01HL135461-01 1/1/2017 Sox6 Role in Renin Expression During Juxtaglomerular Cells Expansion
RH Major, Amy 1R03AI124190-01A1 1/1/2017 Targeting the T cell immune synapse in autoimmunity
EP Hull, Pamela Carmen 1R01CA207401-01A1 12/20/2016 Increasing HPV Vaccine Uptake In Community-Based Pediatric Practices
ID Smith, Scott A. 1R21AI123307-01A1 12/19/2016 Generation And Characterization Of Full-Length Naturally Occurring Allergen-Specific Human IGE MABS
AP Peebles, Ray Stokes 1R01AI124456-01A1 12/6/2016 GLP-1R Signaling In Allergic Inflammation
AP Brummel, Nathan 1K76AG054864-01 9/30/2016 Long Term Outcomes of Physical Activity in Older Adults with Critical Illness
CP Madhur, Meena 1DP2HL137166-01 9/30/2016 Immunophenotyping of Human Hypertension Using Single Cell Multiplex Mass Cytometry to Identify Novel Therapeutic Targets
GE Southard-Smith, E. Michelle  1OT2TR001971-01 9/27/2016 ENSMAP: Molecular and Functional Mapping of the Enteric Nervous System
IM Elasy, Tom 2P30DK092986-07 9/20/2016 Vanderbilt Center for Diabetes Translation Research
HO Johnson, Doug 1K23CA204726-01A1 09/20/2016 Predicting and profiling long-term survival after immune checkpoint inhibition
DE Powers, Al 1UC4DK112232-01 09/20/2016 Integrated Program for Human Pancreas Procurement and Analysis
GE Ruderfer, Douglas 1R01MH111776-01 09/20/2016 Transcriptional Consequences Of Structural Variation In Brains Of Schizophrenia Patients
EP Shu, XIAO-Ou 1P20CA210300-01 09/20/2016 Regional Center of Research Excellence in Cancer and Other Non-Communicable Disease Epidemiology and Prevention in Vietnam
IM Birdee, Gurjeet Singh 1R61AT009340-01 09/15/2016 Breathing Interventions for Relaxation: Dosing through Extended Exhale
NP Breyer, Rich 1R56HL127218-01A1 09/15/2016 PGE2 signaling in Hypertension: The role of EP receptors in the immune system
EP Fowke, Jay 1P20DK112080-01 09/15/2016 Vanderbilt Developmental Center for Translational Research in Benign Urologic Diseases
CA Segrest, Jere 1P01HL128203-01A1 09/15/2016 Multidisciplinary Approaches to HDL Structure, Assembly and Function
DE Wellons, Melissa Fair 1R03HL135453-01 09/15/2016 Trajectory of Anti-Mullerian Hormone Decline and CVD Risk in CARDIA Women
CA Beckman, Joshua 1R01HL131977-01 09/07/2016 The Impact of Diabetes on Revascularization in BEST-CLI
ID Kalams Spryos 1R21AI127129-01 09/05/2016 Molecular analysis of the adaptive immune response to tuberculosis
AP Blackwell, Tim 1R01HL131906-01 09/01/2016 Imaging Activated Macrophages in the Lungs
ID Aronoff, David M. 1R21TR001723-01 09/01/2016 Repurposing misoprostol for Clostridium difficile colitis as identified by PheWAS
CA Wang, Tommy 1R01HL133860-01 09/01/2016 Tissue Sodium, Inflammation, and Blood Pressure in MESA

Other AWARDS (New, Competing)

Agency

Div

Principal Investigator(s)

Agency Serial

Start Date

Title

Department of Defense AP Blackwell, Timothy W81XWH-17-1-0442 09-30-2017 Herpesviruses and Immune Dysregulation in Pulmonary Fibrosis
Department of Defense AP Polosukhin, Vasiliy V. W81XWH-17-1-0503 09-15-2017 Constrictive Bronchiolitis in Previously Deployed Soldiers
Edward P. Evans Foundation HO Savona, Michael R.   09-01-2017 The Role of MCL-1 in Myelodysplasic Syndromes
Cardiovascular Medical Research and Education Fund AP Hemnes, Anna R.   09-01-2017 Imatinib in Pulmonary Arterial Hypertension
Congressionally Directed Medical Research Programs HO Haake, Scott M. CA160728P2 09-01-2017 CA160728P2: Prognostic and Predictive Markers of Immunogenicity in Renal Cell Carcinoma
Congressionally Directed Medical Research Programs HO Rathmell, Wendy K. CA160728P1 09-01-2017 CA160728P1: Prognostic and Predictive Markers of Immunogenicity in Renal Cell Carcinoma
 Bayer NP Harris, Ray   08/02/2017 Bayer Pharma AG Research Collaboration
Foundation for Women & Girls with Blood Disorders HO Sharma, Deva   2017 FWGBD Research Award Program 07-01-2017 Epidemiologic study of acute vaso-occlusive pain associated with menstruation
American Heart Association CP Xiao, Liang   17SDG33670829 07-01-2017 Sympathetic regulation of memory T cells in repeated hypertension
American Heart Association CA Wells, Quinn S. 17IBDG33780015 07-01-2017 Genomics-based Drug Repurposing and Drug Target Discovery in Heart Failure with Preserved Ejection Fraction
Cystic Fibrosis Foundation AP Noto, Michael J. NOTO17Q0 07-01-2017 Broad-spectrum suppression of bacterial pneumonia by A. baumannii mutants
The Stanley Cohen Innovation Fund ID Smith, Scott   07-01-2017 Therapeutic repurposing of naturally occurring human peanut-specific IgE monoclonal antibodies
Susan G. Komen Breast Cancer Foundation RH Edwards, Deanna  PDF17480733 06-13-2017 Targeting the EphA2-YAP/TAZ Signaling Axis in Human Breast Cancer
March of Dimes ID Aronoff, David M. 6-FY17-295 06-01-2017 Defining Macrophage contributions to immune responses during chorioamnionitis
Bristol-Myers Squibb Company CA Moslehi, Javid J. 33256097 05-12-2017 Education Program: To Improve awareness and management of myotoxicity in patients receiving immune checkpoint inhibitors
Doris Duke Charitable Foundation CA Lindman, Brian R. 2014106 04-26-2017 Novel Prediction Models for Patient-Centered Clinical Outcomes after Transcatheter Aortic Valve Replacement for Aortic Stenosis
United States Department of Agriculture EP Hull, Pamela C. 2017-68001-26352 04-15-2017 Children Eating Well (CHEW) Smartphone Application for WIC Families
American Heart Association CP Brown, Nancy J. 17SFRN33520059 04-01-2017 Toward Obesity Precision Medicine: Promise of the Glucagon-Like Peptide 1 Receptor:  Clinical Project
American Heart Association DE Niswender, Kevin D. 17SFRN33520017 04-01-2017 Toward Obesity Precision Medicine: Promise of the Glucagon-Like Peptide 1 Receptor
American Heart Association GE Cox, Nancy J. 17SFRN33590035 04-01-2017 Toward Obesity Precision Medicine: Promise of the Glucagon-Like Peptide 1 Receptor:  Translational Project
American Heart Association DE Niswender, Kevin D. 17SFRN33560015 04-01-2017 Toward Obesity Precision Medicine: Promise of the Glucagon-Like Peptide 1 Receptor:  Center Director
Burroughs Wellcome Foundation NP Bhave, Gautam B. 1017321 01/07/2017 ASMB/Vanderbilt Workshop on Basement Membranes
American Heart Association CP Itani, Hana A. 17SDG33410261 01/01/2017 The Role of Immunological Memory in Hypertension
American Heart Association/Greater Southeast Affiliate CP Gomez-Hurtado, Maria De Las Nieves 17POST33370021 01/01/2017 Calmodulin in Sudden Cardiac Death
V Foundation for Cancer Research DE Blind, Raymond D. 000 11/01/2016 Nuclear lipids as hepatocellular carcinoma biomarkers
V Foundation for Cancer Research HO Balko,J ustin Micah V2016-012 11/01/2016 Maximizing neo-antigens in cancer by epigenetic modulation: improving responses to immunotherapy
American Association for Cancer Research HO Croessmann, Sarah   11/01/2016 SABCS Clinical Scholars Award
Congressionally Directed Medical Research Programs CA Hatzopoulos, Antonis W81XWH-16-1-0622 09/01/2016 PR151029P1 Cellular plasticity in the diabetic myocardium
Pfizer Foundation GI Schwartz, David A. 000 09/01/2016 IBD Visiting Professorship - Grand Rounds Speakers
Congressionally Directed Medical Research Programs HO Morgans, Alicia K. W81XWH-16-1-0554 09/01/2016 PC150398 Patient-Centered Treatment Decision-Making in Advanced Prostate Cancer