Thomas R. Talbot, M.D.

Associate Professor of Medicine

Chief Hospital Epidemiologist, VUMC


Infectious Diseases


M.D. - Vanderbilt University

M.P.H. - Vanderbilt University

BA - Duke University, 1992



Vanderbilt University, 1999-2000; 2001-2003

Thomas R. Talbot, M.D.

Research Focus:

Research Description 

Dr. Talbot is a recognized expert in the field of healthcare epidemiology and infection control, as he currently serves as a member of the Centers for Disease Control and Prevention's Healthcare Infection Control Practices Advisory Committee (HICPAC) and recently served on the Board of Directors for the Society for Healthcare Epidemiology of America (SHEA). He also serves on the Editorial Board for Infection Control and Hospital Epidemiology, the preeminent journal in the field. Dr. Talbot's clinical research is centered on the area of healthcare epidemiology and infection control. He has a particular interest in vaccination of healthcare workers and the prevention of healthcare-associated infections. Dr. Talbot has more than 70 publications in peer-reviewed journals, with original research studies focusing on healthcare personnel vaccination, HAI surveillance, and improving hand hygiene as a tool to drive a culture of safety. As a part of his role as the Chief Hospital Epidemiologist, he oversees the surveillance and prevention of healthcare-associated infections (HAI) at VUMC, including the development of education for staff and physicians and the implementation of quality improvement interventions designed to reduce patient morbidity and mortality related to HAIs.

Honors and Awards 

The Albert Weinstein Prize in Medicine, 1996

lDean's Award, Distinguished by Outstanding Contribution of Leadership and Service, Vanderbilt Medical School, 1996

Alpha Omega Alpha, inducted 1995

SHEA Travel Award, 13th Annual Meeting, 2003

Fellow Teaching Award, Vanderbilt University Division of Infectious Diseases, 2003

ISDA Travel Award, 41st Annual Meeting, 2003

Chief Fellow, Vanderbilt University Division of Infectious Diseases, 2002-2003

Jonathan Freeman Scholarship, Society for Healthcare Epidemiology of America (SHEA), May 2002

IDSA Travel Award, 39th Annual Meeting, 2001

Elliot Newman Prize for Best Clinical Research Paper, Vanderbilt University Department of Medicine, 2005

Tennesseans Improving Patient Safety Award, 2005. Awarded for the project "Standardization of the Central Venous Catheter Insertion Process reduces Catheter Associated Bloodstream Infections." Program Committee Choice Award for Top Abstract, Infectious Diseases Society of America 43rd Annual Meeting, San Francisco, CA, October 2005

Centers for Disease Control and Prevention Citation, Association of Professionals in Infection Control and Epidemiology Annual Meeting, Baltimore, MD, June 2005

National Institutes of Health Clinical Loan Repayment Award, July 2004 - June 2006

Citation for Excellence in Clinical Research, Vanderbilt University School of Medicine Department of Medicine, 2002-2003

Research Keywords 

Hospital Epidemiology, Infection Control, Vaccines, Healthcare-associated Infections


Talbot TR, Johnson JG, Anders T, Hayes RM. Comparison of NHSN-defined central venous catheter day counts with a method that accounts for concurrent catheters. Infect Control Hosp Epidemiol. 2015 Jan; 36(1): 107-9. PMID: 25627768, PII: S0899823X14000075, DOI: 10.1017/ice.2014.7, ISSN: 1559-6834. Available from:, 2015.

Kaye KS, Anderson DJ, Cook E, Huang SS, Siegel JD, Zuckerman JM, Talbot TR. Guidance for infection prevention and healthcare epidemiology programs: healthcare epidemiologist skills and competencies. Infect Control Hosp Epidemiol. 2015 Apr; 36(4): 369-80. PMID: 25998192, PII: S0899823X14000798, DOI: 10.1017/ice.2014.79, ISSN: 1559-6834. Available from:, 2015.

Talbot TR, Carr D, Lee Parmley C, Martin BJ, Gray B, Ambrose A, Starmer J. Sustained Reduction of Ventilator-Associated Pneumonia Rates Using Real-Time Course Correction With a Ventilator Bundle Compliance Dashboard. Infect Control Hosp Epidemiol [print-electronic]. 2015 Nov; 36(11): 1261-7. PMID: 26260255, PII: S0899823X15001804, DOI: 10.1017/ice.2015.180, ISSN: 1559-6834. Available from:, 2015.

Daniels TL, Talbot TR. Infection control and prevention considerations. Cancer Treat. Res. 2014; 161: 463-83. PMID: 24706234, DOI: 10.1007/978-3-319-04220-6_15, ISSN: 0927-3042. Available from:, 2014.

Self WH, Mickanin J, Grijalva CG, Grant FH, Henderson MC, Corley G, Blaschke Ii DG, McNaughton CD, Barrett TW, Talbot TR, Paul BR. Reducing blood culture contamination in community hospital emergency departments: a multicenter evaluation of a quality improvement intervention. Acad Emerg Med. 2014 Mar; 21(3): 274-82. PMID: 24628752, PMCID: PMC3984048, DOI: 10.1111/acem.12337, ISSN: 1553-2712. Available from:, 2014.

Self WH, Talbot TR, Paul BR, Collins SP, Ward MJ. Cost analysis of strategies to reduce blood culture contamination in the emergency department: sterile collection kits and phlebotomy teams. Infect Control Hosp Epidemiol [print-electronic]. 2014 Aug; 35(8): 1021-8. PMID: 25026619, PMCID: PMC4100213, DOI: 10.1086/677161, ISSN: 1559-6834. Available from:, 2014.

Talbot TR. Update on immunizations for healthcare personnel in the United States. Vaccine [print-electronic]. 2014 Aug 8/27/2014; 32(38): 4869-75. PMID: 24231439, PII: S0264-410X(13)01499-0, DOI: 10.1016/j.vaccine.2013.10.090, ISSN: 1873-2518. Available from:, 2014.

Talbot TR, Wang D, Swift M, St Jacques P, Johnson S, Brinsko V, Thayer V, Dail T, Feistritzer N, Polancich S. Implementation of an enhanced safety-engineered sharp device oversight and bloodborne pathogen protection program at a large academic medical center. Infect Control Hosp Epidemiol [print-electronic]. 2014 Nov; 35(11): 1383-90. PMID: 25333433, DOI: 10.1086/678417, ISSN: 1559-6834. Available from:, 2014.

Self WH, Speroff T, Grijalva CG, McNaughton CD, Ashburn J, Liu D, Arbogast PG, Russ S, Storrow AB, Talbot TR. Reducing blood culture contamination in the emergency department: an interrupted time series quality improvement study. Acad Emerg Med. 2013 Jan; 20(1): 89-97. PMID: 23570482, PMCID: PMC3623801, DOI: 10.1111/acem.12057, ISSN: 1553-2712. Available from:, 2013.

Talbot TR, Talbot HK. Influenza prevention update: examining common arguments against influenza vaccination. JAMA. 2013 Mar 3/6/2013; 309(9): 881-2. PMID: 23334755, PII: 1558460, DOI: 10.1001/jama.2013.453, ISSN: 1538-3598. Available from:, 2013.

Esbenshade JC, Edwards KM, Esbenshade AJ, Rodriguez VE, Talbot HK, Joseph MF, Nwosu SK, Chappell JD, Gern JE, Williams JV, Talbot TR. Respiratory virus shedding in a cohort of on-duty healthcare workers undergoing prospective surveillance. Infect Control Hosp Epidemiol [print-electronic]. 2013 Apr; 34(4): 373-8. PMID: 23466910, PMCID: PMC3730277, DOI: 10.1086/669857, ISSN: 1559-6834. Available from:, 2013.

Halasa NB, Grijalva CG, Arbogast PG, Talbot TR, Craig AS, Griffin MR, Schaffner W. Nearly complete elimination of the 7-valent pneumococcal conjugate vaccine serotypes in Tennessee. Pediatr. Infect. Dis. J. 2013 Jun; 32(6): 604-9. PMID: 23348816, DOI: 10.1097/INF.0b013e318287fe0d, ISSN: 1532-0987. Available from:, 2013.

Talbot TR, Johnson JG, Fergus C, Domenico JH, Schaffner W, Daniels TL, Wilson G, Slayton J, Feistritzer N, Hickson GB. Sustained improvement in hand hygiene adherence: utilizing shared accountability and financial incentives. Infect Control Hosp Epidemiol [print-electronic]. 2013 Nov; 34(11): 1129-36. PMID: 24113595, DOI: 10.1086/673445, ISSN: 1559-6834. Available from:, 2013.

Johnson JG, Saye EJ, Jimenez-Truque N, Soper N, Thomsen I, Talbot TR, Creech CB. Frequency of disinfectant resistance genes in pediatric strains of methicillin-resistant Staphylococcus aureus. Infect Control Hosp Epidemiol [print-electronic]. 2013 Dec; 34(12): 1326-7. PMID: 24225622, PMCID: PMC3965576, DOI: 10.1086/673983, ISSN: 1559-6834. Available from:, 2013.

Self WH, Speroff T, McNaughton CD, Wright PW, Miller G, Johnson JG, Daniels TL, Talbot TR. Blood culture collection through peripheral intravenous catheters increases the risk of specimen contamination among adult emergency department patients. Infect Control Hosp Epidemiol [print-electronic]. 2012 May; 33(5): 524-6. PMID: 22476282, DOI: 10.1086/665319, ISSN: 1559-6834. Available from:, 2012.

Rosenbloom ST, Daniels TL, Talbot TR, McClain T, Hennes R, Stenner S, Muse S, Jirjis J, Purcell Jackson G. Triaging patients at risk of influenza using a patient portal. J Am Med Inform Assoc [print-electronic]. 2012 Jul; 19(4): 549-54. PMID: 22140208, PMCID: PMC3384102, PII: amiajnl-2011-000382, DOI: 10.1136/amiajnl-2011-000382, ISSN: 1527-974X. Available from:, 2012.

Talbot TR, Babcock H, Cotton D, Maragakis LL, Poland GA, Septimus EJ, Tapper ML, Weber DJ. The use of live attenuated influenza vaccine (LAIV) in healthcare personnel (HCP): guidance from the Society for Healthcare Epidemiology of America (SHEA). Infect Control Hosp Epidemiol. 2012 Oct; 33(10): 981-3. PMID: 22961016, DOI: 10.1086/667772, ISSN: 1559-6834. Available from:, 2012.

Zuckerman SL, Parikh R, Moore DC, Talbot TR. An evaluation of immediate-use steam sterilization practices in adult knee and hip arthroplasty procedures. Am J Infect Control [print-electronic]. 2012 Nov; 40(9): 866-71. PMID: 22364918, PII: S0196-6553(11)01310-1, DOI: 10.1016/j.ajic.2011.11.006, ISSN: 1527-3296. Available from:, 2012.

May AK, Daniels TL, Obremskey WT, Kaiser AB, Talbot TR. Steroids in the treatment of group A streptococcal necrotizing soft tissue infection. Surg Infect (Larchmt) [print-electronic]. 2011 Feb; 12(1): 77-81. PMID: 21171810, DOI: 10.1089/sur.2010.035, ISSN: 1557-8674. Available from:, 2011.

Dortch MJ, Fleming SB, Kauffmann RM, Dossett LA, Talbot TR, May AK. Infection reduction strategies including antibiotic stewardship protocols in surgical and trauma intensive care units are associated with reduced resistant gram-negative healthcare-associated infections. Surg Infect (Larchmt) [print-electronic]. 2011 Feb; 12(1): 15-25. PMID: 21091186, DOI: 10.1089/sur.2009.059, ISSN: 1557-8674. Available from:, 2011.

Speroff T, Ely EW, Greevy R, Weinger MB, Talbot TR, Wall RJ, Deshpande JK, France DJ, Nwosu S, Burgess H, Englebright J, Williams MV, Dittus RS. Quality improvement projects targeting health care-associated infections: comparing Virtual Collaborative and Toolkit approaches. J Hosp Med [print-electronic]. 2011 May; 6(5): 271-8. PMID: 21312329, DOI: 10.1002/jhm.873, ISSN: 1553-5606. Available from:, 2011.

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Vanderbilt University, 1999-2000; 2001-2003


Residency, Johns Hopkins School of Medicine 1996-1999 Chief Residency, Johns Hopkins School of Medicine, 2000-2001